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Index > Protein center > Myc(Gene name) > Mouse
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  • Myc (Gene name),
  • Myc proto-oncogene protein (Protein name ),  MYC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Myc;
    Protein name:
    Myc proto-oncogene protein;
    Alternative:
    Transcription factor p64;Proto-oncogene c-Myc;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C. Interacts with PARP10. Interacts with KDM5A and KDM5B. Interacts (when phosphorylated at Thr-58 and Ser-62) with FBXW7 (By similarity). Interacts with SPAG9. Interacts with PIM2.
    Function:
    Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
    Subcellular Location:
    Nucleus nucleoplasm Nucleus nucleolus
    Protein Attributes:
    Sequence length:
    439
    Sequence:
    50:
    MPLNVNFTNR | NYDLDYDSVQ | PYFICDEEEN | FYHQQQQSEL | QPPAPSEDIW | 
    100:
    KKFELLPTPP | LSPSRRSGLC | SPSYVAVATS | FSPREDDDGG | GGNFSTADQL | 
    150:
    EMMTELLGGD | MVNQSFICDP | DDETFIKNII | IQDCMWSGFS | AAAKLVSEKL | 
    200:
    ASYQAARKDS | TSLSPARGHS | VCSTSSLYLQ | DLTAAASECI | DPSVVFPYPL | 
    250:
    NDSSSPKSCT | SSDSTAFSPS | SDSLLSSESS | PRASPEPLVL | HEETPPTTSS | 
    300:
    DSEEEQEDEE | EIDVVSVEKR | QTPAKRSESG | SSPSRGHSKP | PHSPLVLKRC | 
    350:
    HVSTHQHNYA | APPSTRKDYP | AAKRAKLDSG | RVLKQISNNR | KCSSPRSSDT | 
    400:
    EENDKRRTHN | VLERQRRNEL | KRSFFALRDQ | IPELENNEKA | PKVVILKKAT | 
    439:
    AYILSIQADE | HKLTSEKDLL | RKRREQLKHK | LEQLRNSGA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290m
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    96T
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    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290r
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    96T
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    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290d
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    96T
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    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290h
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    MSDS:
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    96T
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    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290p
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    MSDS:
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    96T
    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290c
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    MSDS:
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    96T
    ELISA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    E1290b
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    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Myc proto-oncogene protein
    Cat.:
    U1290b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Cat.:
    P1290Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Cat.:
    P1290Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Cat.:
    P1290Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Monoclonal Antibody for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein
    Protein for Mouse Myc proto-oncogene protein

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    References
    1. 1.
      "Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours."
      Bernard O. , Cory S. , Gerondakis S. , Webb E. , Adams J.M.
      EMBO J.2:2375-2383(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
      tissue: Spleen.
    2. 2.
      "Nucleotide sequence comparison of normal and translocated murine c-myc genes."
      Stanton L.W. , Fahrlander P.D. , Tesser P.M. , Marcu K.B.
      Nature310:423-425(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Embryo.
      tissue: Mammary gland.
      tissue: Thymus.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary gland.
    5. 5.
      "Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes."
      Neuberger M.S. , Calabi F.
      Nature305:240-243(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-252
    6. 6.
      "Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation."
      Hurlin P.J. , Queva C. , Koskinen P.J. , Steingrimsson E. , Ayer D.E. , Copeland N.G. , Jenkins N.A. , Eisenman R.N.
      EMBO J.14:5646-5659(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    8. 8.
      "JLP: a scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors."
      Lee C.M. , Onesime D. , Reddy C.D. , Dhanasekaran N. , Reddy E.P.
      Proc. Natl. Acad. Sci. U.S.A.99:14189-14194(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPAG9
    9. 9.
      "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors."
      Takahashi K. , Yamanaka S.
      Cell126:663-676(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOTECHNOLOGY
    10. 10.
      "Pim kinase-dependent inhibition of c-Myc degradation."
      Zhang Y. , Wang Z. , Li X. , Magnuson N.S.
      Oncogene27:4809-4819(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-329;MUTAGENESIS OF SER-329;INTERACTION WITH PIM2
    11. 11.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-149;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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